The Unleashed integration allows for selecting orders to send to Unleashed on approval instead of on Dispatch. If this is implemented though it will result in lower stock in Neto that what is available since pulling in stock doesn't' account for unpicked orders sent to Unleashed reducing the warehouse qty Unleashed sends during a stock pull.
This means the setting is currently only useful when the stock is not being tracked within Neto. If the stock pull accounted for uncommitted orders exported to Unleashed already, the setting would allow for Unleashed to be used to account for orders created but not yet dispatched when determining available stock.